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What's Cholesterol Got to Do With It?

This article in the New York Times reflects the rapid disintegration of the medical orthodoxy that states cholesterol is a key cause of heart disease. In the wake of drug trials that show the drug Vytorin lowers cholesterol levels but not heart risks, an increasing number of doctors are examining the evidence and finding it lacking.

The very language used to discuss heart disease confuses the cholesterol carried in the bloodstream with the particles, known as lipoproteins, that actually carry it. Some of these lipoproteins may pose dangers, but whether or not the cholesterol itself does is much more questionable.

In fact, studies have shown that total cholesterol levels are not a risk factor for coronary heart disease at all, and the cholesterol in low-density lipoproteins is a “marginal risk factor”. A large percentage of people who suffer heart attacks have low levels of low-density lipoproteins.

The main reason cholesterol is assumed to be bad actually comes from circular logic: saturated fat was assumed to be bad because it raises LDL cholesterol, and LDL cholesterol was assumed to be bad because it is the thing that saturated fat raises. But researchers have been unable to generate compelling evidence that saturated fat in the diet causes heart disease.



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Article's Comment     ( 13 Comments )
 
 
 +16 Points           
 
Author of the Article
BY foxtroter   
  
[ Joined on 09/06 ]
[ Posted on January 28, 2008 ]
Post Reply
The good news is that drug companies have made their huge profits before the evidence began to pour in that the hypothesis of lowering cholesterol through drugs was bogus to begin with.

It has been known for years that increasing Omega-3 and decreasing Omega-6 fatty acids to obtain a better ratio has dramatic effect on decreasing the inflammatory state of blood vessels.  Smooth walled blood vessels from a decreased inflammatory state are thought to be not as "sticky or rough" thus not allowing cholesterol to accumulate.  This might be a better hypothesis than the drug company approach.

Oh and remember that the liver makes the majority of cholesterol circulating in the blood and much of it comes from over indulgence in--drum roll again please for Russ--HFCS.

And remember that hyperinsulinemia causes increased inflammatory state in arteries--and a second drum roll for Russ--yes HFCS does increase insulin levels. 
 

 +3 Points           
 
Author of the Article
BY Russ Bianchi   
  
[ Joined on 09/06 ]
Author of the Article [ Posted on January 28, 2008 ]
 
To 'The Wizard Of Oz' theme Tune:

Somewhere, over the corn fields,
Skies are gray
If you believe your Uncle Sam
You'll be in an early grave....

 
 +11 Points           
 
Author of the Article
BY Phantom O' Banjo   
  
[ Joined on 09/06 ]
[ Posted on January 28, 2008 ]
Post Reply
Well imagine that they can't manufacture evidence saturated fat causes heart disease. Pemmican hear I come!

 
 +9 Points           
 
Author of the Article
BY Phantom O' Banjo   
  
[ Joined on 09/06 ]
[ Posted on January 28, 2008 ]
Post Reply
Hey Russ this is for you a sing along!  What cholesterol got to do with it absolutely nothing!
 

 +5 Points           
 
Author of the Article
BY Russ Bianchi   
  
[ Joined on 09/06 ]
Author of the Article [ Posted on January 28, 2008 ]
 
To Sachmo's Version Of 'What A Wonderful World':

"I see corn a-golden,
 Refineries too
 I see profit
 For Uncle Sam, not you

 And I think to myself
 What a screwed up world....

 I see skies a brown
 And clouds a black
 The dark damned day
 The nucelar lit night

 And I think to myself
 What a screwed up world...

 The glow of the neon rainbow
 So iffy in the smoggy haze
 Are obscured on the faces
 Of people eating poor...
 I don't hear babies
 Because there are few to grow
 They will lean much more
 Than I'll never know (at Vital Votes)

  And I think to myself
  What a screwed up world....
  Oh, nooooo....."

Sigh,

Uncle Russ


 
 +5 Points           
 
Author of the Article
BY morleyevans